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Pharmaceutical Active Ingredients Pharmaceutical Raw Materials Avanafil CAS 330784-47-9

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Pharmaceutical Active Ingredients Pharmaceutical Raw Materials Avanafil CAS 330784-47-9

China Pharmaceutical Active Ingredients Pharmaceutical Raw Materials Avanafil CAS 330784-47-9 supplier

Large Image :  Pharmaceutical Active Ingredients Pharmaceutical Raw Materials Avanafil CAS 330784-47-9

Product Details:

Place of Origin: China(Mainland)
Brand Name: XinRunde
Certification: GMP
Model Number: 330784-47-9

Payment & Shipping Terms:

Minimum Order Quantity: 5g
Price: Negotiable, Mr. Bruce Li (bruce.xinrunde@yahoo.com )
Packaging Details: 1-2 kg / aluminum foil bag, 25kg/ drum, as required
Delivery Time: 2-4 days after received your payments
Payment Terms: T/T Bank, MoneyGram, Western Union, etc
Supply Ability: 10 000 KG /month
Detailed Product Description
CAS: 330784-47-9 Appearance: White Powder
Usage: Bodybuilding Type: Pharmaceutical Raw Materials
Delivery: By DHL, TNT, FedEx, HKEMS, UPS, Etc Alias: 4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide

Pharmaceutical Active Ingredients Pharmaceutical Raw Materials Avanafil CAS 330784-47-9

 
 

 

Quick Details:

 


 

  • Production Name: Avanafil
  • Alias: 4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide
  • CAS No: 330784-47-9
  • Einecs No:
  • MF: C23H26ClN7O3
  • MW: 483.9506
  • Purity: 99%min
  • Appearance: white powder

 

 

 
 
Product Description:
 
 
For most individuals, the recommended starting dose of avanafil is 100 mg per day taken about 30
 
minutes before sexual Avanafil activity. Depending on the adequacy of the response or side effects, the
 
dose may be increased to 200 mg or decreased to 50 mg a day. Individuals who are taking medications
 
that moderately increase Avanafil the blood levels of avanafil should not exceed a total dose of 50 mg in
 
24 hours.Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various
 
body tissues, but primarily in the corpus cavernosum penis, as well as the retina. Other similar drugs are
 
sildenafil, tadalafil and vardenafil. The advantage of avanafil is that it has very fast on set    of  action
 
 compared  with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about
 
30–45 minutes. About two-thirds of the participants were able to engage in sexual activity within 15
 
minutes.
 

 
 
 

Specifications :
 

 

Water Content: 0.5%max conforms
Specific Rotation: 0.5%max conforms
Residue on Ignition: 0.5%max conforms
Density: 1.020-1.035 1.03
Characteristics: white powder Pass
Solubility: Almost insoluble in water, soluble in vegetable oil Conforms
Specific optical rotation: +28o~+35o +33.4o
Identification: IR,TLC Positive
Heavy Metals: <20PPm 10PPm
Assay: 97.00% 97.13%
Related substances: 3.0%max <3.0%
Free Acid: 0.5%max 0.16%

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Applications:
 
 

 

1.  Avanafil occurs as white crystalline powder, molecular formula C23H26ClN7O3 and molecular weight of
 
483.95 and is slightly soluble in ethanol, practically insoluble in water, and soluble in 0.1 mol/L  
 
hydrochloric acid. for oral administration, is supplied as oval, pale yellow tablets containing 50 mg, 100
 
mg, or 200 mg avanafil debossed with dosage strengths.
 
 
2.  Avanafil is a potent, highly selective phosphodiesterase 5 inhibitor, in vitro experiments showed that

 

the selectivity of phosphodiesterase 5 stronger than . The compound dear compliance weak against other
 
phosphodiesterase, and effect of adenosine receptor decreased, suggesting that the cardiovascular
 
effects of avanafil should be weaker than .
 
 
3.  Pre clinical study showed that avanafil and organic nitrate drugs taken in combination to reduce its on
 
blood pressure was significantly weaker than and nitrate drugs with clothes. Moreover, avanafil inhibition
 
of phosphodiesterase 6 is very weak, the relevant visual disturbance suppression may the enzyme
 
phosphodiesterase 5 inhibitor induced and other.

 


 
 
Pharmaceutical Active Ingredients Pharmaceutical Raw Materials Avanafil CAS 330784-47-9
 
 
 
 
Advantages:
 
Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.

 

1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are

allowed to sell.

 

2. Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within

24 hours after receiving the payment Lead time 4 or 7 days.

 

3.  Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate.

 

4.  Warm after-sale service Any of your question would be solved for the first as soon as possible.
 

 

 
Pharmaceutical Raw Materials Avanafil white powder CAS NO 330784-47-9

 

Contact Details
Hubei XinRunde Chemical Co., Ltd

Contact Person: Bruce Li

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